We are interested in interfaces between biological materials and inorganic surfaces. Especially, we employ two-dimensional (2D) nanosheets as the inorganic surface because of their unique physical properties. In our previous researches, we have developed several types of peptides which have abilities to form ordered nanostructures on those 2D nanosheets, and understood the mechanism of their interactions in the manner of self-assembly and (opto-)electronics.

Recently, we found that self-organized peptides can modulate the electronic properties of single-layer graphene depending on their peptide sequence and surface morphology. This work was introduced at this web site (UW-Today). We have been collaborating with the UW team since 2009.

Currently, we are intensively working on establishing a novel bio-nano system which allows us to communicate with a cell by using our platforms based on the 2D nanosheets.Our interdisciplinary research field contains variety of fundamental science, i.e., Self-assembly, electronics, optics, electrochemistry, surface science, biomaterials, and biophysics. Conbining all the fundamentals, we challenge to develop a novel functional system with hierarchical assemlby of multiple components and materials. The hierarchical function has already been done in natural biological systems, but still the challenge is how to involve electronics in this picture.


Research Topics

1) Material innovation: New design of peptide sequences and the control of self-assembly of bio-materials (peptides and proteins) on solid surfaces.

C. R. So, Y. Hayamizu, H. Yazici, C. Gresswell, D. Khatayevich, C. Tamerler, and M. Sarikaya, “Controlling Self Assembly of Engineered Peptides on Graphite by Rational Mutation,” ACS Nano, 6 (2) 1648-1656 (2012)


2) Design of electronic devices using nano-materials (graphene and others) functionalized by bio-materials in nano-scale.

Hayamizu, Y., So, C., Dag, S., Page, T. S., Starkebaum, D., &Sarikaya, M. "Bioelectronic interfaces by spontaneously organized peptides on 2D atomic single layer materials." Scientific Reports 6, Article number: 33778 (2016)

3) Understanding of the self-assembly of peptides and proteins on solid surfaces.

4) Developments of novel characterization techniques for understanding the bio-nano interfaces.

5) Understanding of mechanisms in energy transfer between bio-materials and nano-materials.

6) Developments of novel system to communicate with cells via electrochemical signals by 2D nanosheets.



Micro ElectroMechanical Systems (MEMS) made by Carbon Nanotubes.

Nature Nanotechnology (2009)

@AIST, Japan

Self-Assembled Peptides on Graphite

ACS NANO (2012)

@Sarikaya Group, University of Washington